Description
Alpha-2-macroglobulin (A2M) is a major serum protein with diverse functions, including inhibition of protease activity and binding of growth factors, cytokines, and disease factors. Increased alpha-2-macroglobulin in serum has been suggested to be associated with multiple sclerosis (MS), glomerular disease, and liver diseases. Mouse alpha-2-macroglobulin is believed to be a functional homologue of human alpha-2- macroglobulin